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Long-Term Smoking Cessation Improves Bladder Cancer Outcomes

August 24, 2012   Long-term smoking cessation may attenuate the detrimental effect of cigarette smoking on oncologic outcomes among patients who undergo surgery for non-muscle-invasive bladder cancer (NMIBC), a study found. The study included 2,054 patients with NMIBC who underwent transurethral resection of the bladder. Former smokers who had stopped smoking 10 or more years prior to surgery had a 34% decreased risk of disease recurrence and a 58% decreased risk of progression compared with current smokers, researchers reported online in European Urology. The study, led by Shahrokh F. Shariat, MD, of Weill Medical College of Cornell University in New York, also showed that compared with patients who never smoked, current and former smokers have a 22% and 12% increased risk of disease recurrence, respectively, and a twofold and 29% increased risk for disease progression, respectively.

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